Using Carbon Dioxide as a Building Block in Continuous Flow Synthesis

Advanced Synthesis and Catalysis 361(2), 247-264, DOI: 10.1002/adsc.201801228

Carbon dioxide (CO2) is an attractive building block for organic synthesis that is environmentally friendly. Continuous flow technologies have enabled C−O and C−C bond forming reactions with CO2 that previously were either low-yielding or impossible in batch to afford value-added chemicals. This review describes recent advances in continuous flow as an enabling strategy in utilizing CO2 as a C1 building block in chemical synthesis.